Research Interests / Areas of Expertise:
Dr. Randic investigates chemical synaptic transmission and plasticity in the mammalian spinal cord in a normal state and following tissue or nerve injury. She also researches regulation of release, receptors and ion channels on excitatory amino acids by neuropeptides, G-proteins and second messengers.


Education & Certifications:
M.D.: University of Zagreb (Yugoslavia), 1962.
Ph.D.: University of Zagreb (Yugoslavia), 1962.


Teaching:
Research Review -- BMS 688


Selected Publications:
Ikeda, H., Asai, T., Randic, M., and Murase, K. Robust suppression of afferent-induced excitation in the rat spinal dorsal horn after conditioning low-frequency afferent A-fibers stimulation. J Neurophysiol (in press).

Randic, M., Zhng, J., Gerber, G., and Kojic, L.J. Dual modulation of excitatory synaptic transmission by agonists at Group I metabotropic glutamate receptors in the rat spinal dorsal hor. J Neurosci (in press).

Hocherman, S.D. and Randic, M. Reduction of NMDA-induced Ca²⁺ transients by a m-opioid receptor agonist in dorsal horn neurons. Neuro Report 8:3061-3065, 1997.

Sandkohler, J., Chen, J.G., Cheng, G., Randic, M. Low-frequenc stimulatin of afferent Ad-fibers induces long-term depression at primary afferent synapses with substantia gelatinosa neurons in the rat. J Neurosci 17:6483-6491, 1997.

Kolaj, M. and Randic, M. m-Opioid receptor-mediated reduction of AMPA-activated current in dorsal horn neurons. Neurosci Lett 204:133-137, 1996.

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