Research Interests / Areas of Expertise:
Dr. Rosenbusch investigates molecular events in mycoplasmal and bacterial infection of ruminants, emphasizing bovine respiratory disease and pinkeye. This includes virulence attributes of ruminant mycoplasmas, epidemiological studies of respiratory mycoplasma infections, and vaccine development.

Education & Certifications:
D.V.M.: University of Buenos Aires, 1964.
M.S.: Iowa State University, 1966.
Ph.D.: Iowa State University, 1969.
Diplomate: American College of Veterinary Microbiologists.

Teaching:

VMPM 378, Case Studies IV; Instructor

VMPM 536, Zoonoses; selected lectures

Contribute laboratory experiences for VMPM 386

Lectures for VMPM 536; Zoonoses.

Offer undergraduate research experiences for Microbiology students (Micro 490).


Selected Publications:
Harvey, M. E., D. E. Morrical, and R. F. Rosenbusch. Sheep flock infections with Mycoplasma ovipneumoniae involve multiple strains. (Accepted, Small Ruminant Res.)

Hauer, P. J., T. J. Yeary, and R. F. Rosenbusch. 2006. Evidence of the protective immunogenicity of Clostridium haemolyticum phospholipase C (beta toxin) in guinea pigs. Vaccine 24: 124-132.

Rosenbusch, R. F. 2005. Transmission of Mycoplasma bovis and the syndromes that result in beef and dairy cattle. Proceedings of the American Association of Bovine Practitioners. 38: 1-5.

Rosenbusch, R. F., Kinyon, J. M., Apley, M., Funk, N. D., Smith, S., and L. J. Hoffman. 2005. In vitro antimicrobial inhibition profiles of Mycoplasma bovis isolates recovered from various regions of the United States from 2002-2003. J. Vet. Diagn. Invest. 17:436-441.

Lu, X., and R. F. Rosenbusch. 2004. Endothelial cells from bovine pulmonary microvasculature respond to Mycoplasma bovis preferentially with signals for mononuclear cell transmigration. Molecular Pathogenesis 37: 253-261.

Stabel, J. R., Hurd, S., Calvente, L., and R. F. Rosenbusch. 2004. destruction of Mycobacterium paratuberculosis, Salmonella spp., and Mycoplasma spp. in raw milk by a commercial on-farm high-temperature, short-time pasteurizer. J. Dairy Sci 87: 2177-2183.

Hauer, P. J., Yeary, T. J., and R. F. Rosenbusch.2004. Cloning and molecular characterization of the Beta toxin (Phospholipase C) gene of Clostridium haemolyticum. Anaerobe 10: 243-254.

Vanden Bush, T. J. and R. F. Rosenbusch. 2004. Characterization of a lympho-inhibitory peptide produced by Mycoplasma bovis. Bioch. Biophys. Res. Comm. 315: 336-341.

Vanden Bush, T. J., and R. F. Rosenbusch. 2003. Characterization of the immune response to Mycoplasma bovis lung infection. Vet. Immunol. Immunopathol. 94: 23-33.

Vanden Bush, T. J., and R. F. Rosenbusch. 2002. Mycoplasma bovis induces apoptosis of bovine lymphocytes. FEMS Immunol. Med. Microbiol. 32: 97-103.

Butler, J. A., C. C. Pinnow, J. U. Thomson, S. Levisohn, and R. F. Rosenbusch. 2001. Use of arbitrarily primed polymerase chain reaction to investigate Mycoplasma bovis outbreaks. Vet. Microbiol. 78: 175-181.

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Leadership:
Reviewer for American Journal of Veterinary Research, 2001-2003. Currently Ad-Hoc Reviewer for Infection and Immunity, American Journal of Veterinary Research, Theriogenology, Journal of Veterinary Diagnostic Investigations, Microbiology, Molecular and Cellular Probes, Molecular Pathogenesis, Vaccine, Veterinary Research, Clinical and Diagnostic Laboratory Immunology, International Journal of Systematic and Evolutionary Microbiology.

Ad-hoc Reviewer for Research Proposals to USDA Special, USDA-NRI Grants, BARD Grants, Wellcome Foundation Grants, Beef Cattle Research Council- Canada, 1987- present.

At-large member of the International Research Program on Comparative Mycoplasmology, a permanent standing committee of the International Organization for Mycoplasmology, 2000-2007.

Member of the Mollicute Taxonomy Subcommittee of the International Committee on Systematics of Prokaryotes, 2000- .

Chair, Immunobiology Graduate Program at ISU, 1999-2005.

Treasurer and Board of Directors Member, International Organization for Mycoplasmology, 1996-2000.

Chair of the Ruminant Mycoplasma Working Team of the International Research Program on Comparative Mycoplasmology, a permanent standing committee of the International Organization for Mycoplasmology, 1994-00.

Honors & Awards:
Phi Beta Delta, Honor Society for International Scholars, 1990
Osborn Research Club, ISU, 1990
Beecham Award for Research Excellence, ISU, 1987
Diploma de Honor, U. of Buenos Aires, 1969
Phi Zeta, Honor Society for Veterinary Medicine, 1966
Gamma Sigma Delta, Honor Society for Agriculture, 1966

Memberships:
Member of the American Veterinary Medical Association
Member of the American Association of Bovine Practitioners
Member of the Conference of Research Workers in Animal Disease
Member of American College of Veterinary Microbiologists
Member of American Society for Microbiology
Member of the International Organization for Mycoplasmology
Member of the American Society for the Advancement of Science