Research Interests / Areas of Expertise:
My research activity stems from an interest in the electrical properties of cells and their responses to drugs. I have developed the Ascaris suum, Oesophagostomum dentatum & Schistosoma mansoni preparations for electrophysiological recording and the examination of the mode of action of anthelmintics which exert their effects on membrane ion-channels. My research interests also include the mode of action of antiparasite drugs and mechanisms of resistance. The neuropharmacology and toxicology of nematode ion channels studied using patch-clamp techniques. Development of new target sites for anthelmintic drugs


Education & Certifications:
B.V.Sc.: University of Liverpool, 1972.
Diploma: Neurophysiology, University of Edinburgh, 1973.
Ph.D.: University of Liverpool, 1977.
D.Sc.: University of Edinburgh, 1997.


Teaching:
Integrative Physiology -- BMS 355


Selected Publications:
Martin, R. J. (2000) Veterinary Parasitology: Developments in Immunology, Epidemiology & Control. Parasitology Today. 16, 44-45.

Martin, R. J. (2000) Veterinary Parasitology: Developments in Immunology, Epidemiology & Control. Parasitology Today. 16, 44-45.

Robertson, A. P., Bjorn, H. and Martin, R.J. (2000) Pyrantel resistance alters nematode nAChR single- channel properties. European Journal of Pharmacology. 394, 1-8.

Martin, R. J. and Robertson, A. P. (2000). Electrophysiological Investigation of Anthelmintic Resistance. Parasitology 37, S87.

R. A. Fellowes, A. G. Maule1, R. J. Martin, M. J. Kimber, N. J. Marks, & D. W. Halton. (2000) Classical neurotransmitters in the ovijector of Ascaris suum: localisation and modulation of muscle activity.Parasitology. 121, 325-336.

Robertson, A. P., Bjorn, H. and Martin, R. J. (1999). Levamisole resistance resolved at the single-channel level.  FASEB Journal.  38, 749-760.

Robertson, A. P., Bjorn, H. and Martin, R.J. (2000) Pyrantel resistance alters nematode nAChR single-channel properties.  European Journal of Pharmacology. 394, 1-8.

Tailovic, S.M., Robertson, A.P., Clark, C.L., & Martin, R.J. (2002).  Levamisole receptor phosphorylation: effects of kinase antagonists on membrane potential responses in Ascaris suum suggest that CaM Kinase and tyrosine kinase regulate sensitivity to levamisole.  J. Exp. Biol 205, 3979-3988.

Martin, R. J., Guanxing B, Clark C. L. & Robertson, A. P. (2003). Methyridine (2-[2-methoxyethyl]-pyridine]) and levamisole activate different ACh receptor subtypes in nematode parasites: a new lead for levamisole-resistance.  British Journal of Pharmacology. 140, 1068-1076

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Leadership:
Elected member of Council, British Society for Parasitology, 1996.

Elected Executive member, Meeting Secretary to the Centre of Parasite Biology, 1996.

Treasurer of the Scottish Membrane Transport Group, 1996.


Honors & Awards:
Elected Fellow of the Royal Society of Medicine


Memberships:
Physiological Society
British Pharmacological Society
Royal College of Veterinary Surgeons
Association for Veterinary Clinical Pharmacology and Therapeutics
European Community Soc. for Vet. Pharmacology & Therapeutics (ECVPT)
Neuroscience
American Association of Veterinary Parasitology