Recent Publications
Choi CJ, Kanthasamy A, Anantharam V, Kanthasamy AG (2006) Interaction of metals with prion protein: possible role of divalent cations in the pathogenesis of prion diseases. Neurotoxicology 27:777-787.
Kanthasamy A, Anantharam V, Ali SF, Kanthasamy AG (2006a) Methamphetamine induces autophagy and apoptosis in a mesencephalic dopaminergic neuronal culture model: role of cathepsin-D in methamphetamine-induced apoptotic cell death. Ann N Y Acad Sci 1074:234-244.
Kanthasamy AG, Anantharam V, Zhang D, Latchoumycandane C, Jin H, Kaul S, Kanthasamy A (2006b) A novel peptide inhibitor targeted to caspase-3 cleavage site of a proapoptotic kinase protein kinase C delta (PKCdelta) protects against dopaminergic neuronal degeneration in Parkinson's disease models. Free Radic Biol Med 41:1578-1589.
Sun F, Anantharam V, Zhang D, Latchoumycandane C, Kanthasamy A, Kanthasamy AG (2006) Proteasome inhibitor MG-132 induces dopaminergic degeneration in cell culture and animal models. Neurotoxicology 27:807-815.
Kanthasamy, AG., Kitazawa, M., Kanthasamy, A and Anantharam, V. (2005). Dieldrin-Induced Neurotoxicity: Relevance to Parkinson's Disease Pathogenesis. Neurotoxicology, 26, 701-19.
Kaul, S, Anantharam, V, Kanthasamy, A and Kanthasamy, AG (2005) Wild-type a-synuclein interacts with pro-apoptotic proteins PKCd and BAD to protect dopaminergic neuronal cells against MPP+-induced apoptotic cell death. Molecular Brain Research 139:137-52.
Sun, F., Anantharam, V., Latchoumycandane, C., Kitazawa, M., Yang, Y., Kanthasamy, A. and Kanthasamy, AG. (2005) Dieldrin Induces Ubiquitin-Proteasome Dysfunction in α-Synuclein Overexpressing Dopaminergic Neuronal Cells and Enhances Susceptibility to Apoptotic Cell Death. J. Pharmacol. Expt. Therapeutics 315:69-79.
Kaul, S, Anantharam, V, Yang, Y, Choi, C, Kanthasamy, A and Kanthasamy, AG (2005) Tyrosine Phosphorylation Regulates the Proteolytic Activation of PKCd In Dopaminergic Neuronal Cells. J. Biol. Chem. 280: 28721-30.
Latchoumycandane, C., Anantharam, V., Kitazawa, M., Yang, Y., Kanthasamy, A. and Kanthasamy, AG. (2005) Protein Kinase C Delta (PKCd) is a key Downstream Mediator of Manganese-induced Apoptosis in Dopaminergic Clonal Cells. J. Pharmacol. Expt. Therapeutics. 313:46-45.
Yang, Y; Kaul, S; Zhang, D; Anantharam, V.; Kanthasamy, A. G. (2004) Suppression of caspase-3 dependent proteolytic activation of protein kinase cdelta by small interfering RNA (siRNA) prevents MPP+-induced dopaminergic degeneration. Molecular and Cellular Neuroscience, 25 (3):406-421.
Tailovic, S.M., Robertson, A.P., Clark, C.L., & Martin, R.J. (2005). Brief application of AF2 produces long lasting potentiation of nAChR responses in Ascaris suum. Mol. Biochem. Parasitol. 139. 51-64.
Levandoski,M.M, Robertson, A. P., Kuiper, S. & Martin, R. J. (2005) Single channel properties of N- and L- subtypes of acetylcholine receptors in Ascaris suum Levandoski, Robertson, Kuiper and Martin Int. J. Parasitol. 1-10
Martin, R. J., Trailovic, S. M., Clark C. L. & Robertson, A. P. (2004). Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole & pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris . Int. J. Parasitol 34, 1083-1090.
